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目的分析不同药物治疗糖尿病周围神经病变的临床效果。方法收集2015年1月-2016年1月该院收治的糖尿病周围神经病变患者74例,随机分为观察组与对照组各37例。观察组给予前列腺素E1、α-硫辛酸治疗,对照组给予常规治疗,对比2组患者治疗前后症状评分及临床疗效。结果治疗后2组患者的症状积分均低于治疗前,且观察组症状积分明显低于对照组;观察组总有效率为86.49%高于对照组的59.46%,差异均有统计学意义(P<0.05)。结论糖尿病周围神经病变患者经α-硫辛酸及前列腺素E1治疗的效果显著,值得临床应用。
Objective To analyze the clinical effect of different drugs on diabetic peripheral neuropathy. Methods Totally 74 patients with diabetic peripheral neuropathy admitted to our hospital from January 2015 to January 2016 were randomly divided into observation group (37 cases) and control group (37 cases). The observation group was treated with prostaglandin E1 and α-lipoic acid, and the control group was given routine treatment. The symptom score and clinical effect of two groups were compared before and after treatment. Results After treatment, symptom scores of two groups were lower than those before treatment, and symptom scores of the observation group were significantly lower than those of the control group. The total effective rate was 86.49% in the observation group and 59.46% in the control group, with significant differences (P <0.05). Conclusion The effect of α-lipoic acid and prostaglandin E1 in patients with diabetic peripheral neuropathy is significant and worthy of clinical application.