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目的 探讨扁桃体树突状细胞肉瘤的临床及病理特点,提高对该病诊治水平。方法 分析扁桃体树突状细胞肉瘤的临床资料及进行组织病理学、免疫组化研究。结果 扁桃体树突状细胞肉瘤无特征性临床表现。组织学表现为瘤细胞呈椭圆形,瘤组织弥漫分布,瘤组织间常夹杂小淋巴细胞。免疫组化标记S-100(±),CD 68(+),Vim(+),手术加化疗随访20个月后局部无复发,无全身其它系统转移。结论 扁桃体树突状细胞肉瘤是一种罕见的低度恶性肿瘤,诊断依赖于组织病理学及免疫组化标记,治疗以手术切除为主,辅以化疗,预后良好。
Objective To investigate the clinical and pathological features of tonsil dendritic cell sarcoma and to improve the diagnosis and treatment of the disease. Methods The clinical data of tonsillar dendritic cell sarcoma and histopathological and immunohistochemical studies were analyzed. Results tonsil dendritic cell sarcoma no specific clinical manifestations. Histological findings showed oval tumor cells, tumor tissue diffuse distribution, tumor tissue often mixed with small lymphocytes. Immunohistochemical markers S-100 (±), CD 68 (+), Vim (+), surgery plus chemotherapy 20 months follow-up local no recurrence, no other systemic systemic metastasis. Conclusions Tonsillar dendritic cell sarcoma is a rare low-grade malignant tumor. The diagnosis depends on histopathology and immunohistochemistry. Surgical resection is the main method of treatment. Chemotherapy is performed with good prognosis.