目的:探讨腹腔镜手术联合药物治疗输卵管妊娠的临床疗效。方法:选择腹腔镜手术治疗输卵管妊娠的104例,以腹腔镜下保守性治疗(腹腔镜下输卵管妊娠物取出,局部系膜下注射甲氨蝶呤)的53例为实验组,以腹腔镜下患侧输卵管切除术的51例为对照组。比较两组治疗效果及术后的血HCG。结果:两组术后血HCG降至正常的时间差异无统计学意义(P>0.05)。实验组输卵管通畅率为75.5%,宫内妊娠率为28.30%,均高于对照组(P<0.05)。结论:腹腔镜手术联合药物治疗输卵管妊娠的临床效果显著,无持续性异位妊娠发生,手术简单易行,具有较好临床实用性。 Objective: To investigate the clinical efficacy of laparoscopic surgery combined with drug treatment of tubal pregnancy. Methods: Laparoscopic surgery in 104 cases of tubal pregnancy, laparoscopic conservative treatment (laparoscopic tubal pregnancy removal, sub-sub-regional injection of methotrexate) in 53 cases as the experimental group, laparoscopic 51 cases of ipsilateral tubal resection for the control group. The treatment effect and postoperative blood HCG were compared between the two groups. Results: There was no significant difference between the two groups in the time of blood HCG normalization (P> 0.05). The rate of tubal patency in the experimental group was 75.5%, intrauterine pregnancy rate was 28.30%, all higher than the control group (P <0.05). Conclusion: Laparoscopic surgery combined with drug treatment of tubal pregnancy clinical results were significant, no persistent ectopic pregnancy occurred, the operation simple and easy, with good clinical practice.