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为减轻因放射引起的皮肤损害,作者研究了60种汉方方剂的甲醇提取物对受损皮肤的保护作用。 6周龄的ICR雄性小鼠全身接受1100R照射,将60种汉方方剂的甲醇提取物于照射前(5min,60min)或照射后(5min,60min)腹腔给药,从给药21~40d内观察小鼠受损皮肤的损害程度,给药组和不给药组都以平均计分表示。结果表明:于照射前5min给药的有效方剂为温清饮、九味槟榔汤、桂枝芍药知母汤、
In order to reduce skin damage caused by radiation, the authors studied the protective effect of methanol extracts of 60 Chinese herbal formulas on damaged skin. Six-week-old ICR male mice were irradiated with 1100R systemically and 60 kinds of methanol extracts were intraperitoneally administered before (5 min, 60 min) or after (5 min, 60 min) irradiation, within 21 to 40 days after administration. The degree of damage to the damaged skin of the mice was observed, and both the administration group and the non-administration group were expressed on average. The results showed that the effective formulas administered 5 min before irradiation were Wenqing Yin, Jiuwei Betel Nut Soup, Guizhi Shaoyao Zhimu Decoction,