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糖尿病、非糖尿病组（对照组）各２３例，分别在人工晶体植入术（ＥＣＣＥ＋ＩＯＬ）前后进行角膜内皮显微镜观察和计算机图像分析。对照组术后３个月角膜内皮细胞（ＣＥＣ）、形状系数（ＦＣ）和变异系数（ＣＶ）恢复正常（Ｐ＞０．０５），以后（至２年）ＣＥＣ密度（Ｄ）未继续下降。而与对照组比较，糖尿病组术前ＣＥＣ面积（Ａ）正常，但周长（Ｐｅ）、长径（Ｌ）、ＣＶ增大，ＦＣ减小（Ｐ＜０．０１）；术后２年内各形态定量指标较术前及同期对照组差异有显著性意义（Ｐ＜０．０５或０．０１），Ｄ持续下降，表明形态定量检测可判断ＥＣＣＥ＋ＩＯＬ术后ＣＥＣ预后状况，尤其对糖尿病患者十分重要。
Diabetic and non-diabetic patients (control group), 23 cases were examined by corneal endothelial microscopy and computer image before and after intraocular lens implantation (ECCE + IOL) respectively. Corneal endothelial cells (CEC), shape factor (FC) and coefficient of variation (CV) returned to normal at 3 months postoperatively in control group (P> 0.05). CEC density (D) did not continue to decline after 2 years. Compared with the control group, preoperative CEC area (A) in diabetic group was normal, but the circumference (Pe), long diameter (L), CV increased and FC decreased (P <0.01) The morphological quantitative indexes were significantly different from those in the preoperative and the control group (P <0.05 or 0.01), and D was continuously decreased, indicating that morphometric detection can predict the prognosis of CEC after ECCE + IOL, especially for patients with diabetes mellitus .