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哮喘持续状态是常见的急诊病状,一般经治疗,多能较快缓解。但少数重度哮喘持续状态者疗效不好,从而进一步加重呼衰,引起肺腑甚至猝死。笔者试用酚妥拉明抢救,取到较好疗效。资料与方法11例均为经输液、静注氨茶硷和激素或吸入β_2-兴奋剂无效,哮喘持续时间12～50小时(平均30小时以上)的急诊病人。按哮喘程度分级指标,11例均符合为重度哮喘持续状态。全部病人排除了慢支及其它心肺疾病。将酚妥拉明10mg加入5%GS500ml中,根据年龄和体重,每分钟控制在30～45滴(即0.04～0.06mg/分钟),5分钟后测血压、心率,防止血压骤降或心率加快。30分钟后观察疗效。
Persistent asthma is a common emergency condition, usually treated, can be more quickly relieved. However, a small number of patients with severe asthma persistent state of efficacy is not good, thus further aggravating respiratory failure, causing heart or even sudden death. I try phentolamine rescue, get better effect. Materials and Methods All 11 cases were emergency patients who were transfused with intravenous injection of aminophylline and hormone or inhaled β_2-stimulants, and whose asthma duration was 12 to 50 hours (mean 30 hours). According to the degree of asthma grading, 11 cases were consistent with severe asthma persistence. All patients ruled out chronic bronchitis and other cardiopulmonary diseases. Phentolamine 10mg added to 5% GS500ml, according to age and body weight, 30 to 45 drops per minute control (ie 0.04 ~ 0.06mg / min), 5 minutes after the blood pressure, heart rate, to prevent sudden drop in blood pressure or heart rate . After 30 minutes to observe the effect.