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Objective:To estimate the impact of autologous transfusion on the status of perioperative immune activation inmalignant tumor patients.The Serum Neopterin and Interleukin-2(IL-2)were measured.Methods:Sixty patients undergoingelective radical resection for malignant stomach tumor were enrolled in the prospective study and assigned to the following groups:(Ⅰ)Group A received autologous transfusion;(2)Group H received allogeneic transfusion.The perioperative course(Beforeinduction of anesthesia,after operation and 5 d after operation)of Neopterin and IL-2 was compared.Results:In group A,SerumNeopterin was significantly lower than baseline alter operation and IL-2 had no significant changes.In group H,both SerumNeopterin and IL-2 were significantly lower than baseline alter operation and 5 d after operation.Compared with group A,SerumNeopterin was significantly lower than baseline alter operation and 5 d after operation and IL-2 was significantly lower thanbaseline 5 d alter operation.Conchision:Autologous
Objective: To estimate the impact of autologous transfusion on the status of perioperative immune activation in malignant tumor patients. The Serum Neopterin and Interleukin-2 (IL-2) were measured. Methods: Sixty patients undergo ingelective radical resection for malignant stomach tumor were enrolled in the prospective study and assigned to the following groups: (1) Group A received autologous transfusion; (2) Group H received allogeneic transfusion. perioperative course (Beforeinduction of anesthesia, after operation and 5 d after operation) of Neopterin and IL-2 was compared.Results: In group A, SerumNeopterin was significantly lower than baseline alter operation and IL-2 had no significant changes.In group H, both SerumNeopterin and IL-2 were significantly lower than baseline alter operation and 5 d after operation. Compared with group A, SerumNeopterin was significantly lower than baseline alter operation and 5 d after operation and IL-2 was significantly lower than baseline 5 d alter operation. Co nchision: Autologous