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目的 作者作了一项病例对照研究以评估无输血史或无毒品注射史患者C型肝炎病毒(HCV)感染的危险因素和可能的传播方式。方法:研究病例选自美国西南部一所大学医疗中心的胃肠病专科门诊患者。在477例HCV抗体检查阳性患者选取58例无输血史或无毒品注射史的慢性HCV感染患者作为研究人群。对照组为在同一门诊诊断为胃食道返流的58例患者,年龄、种族和性别与研究组匹配。分别询问患者组和对照组病史和复习病例记录。结果有多种因素与散发HCV感染显著相关,其中包括纹身史,针刺史、性传播疾病史、与毒品注射者有性
The authors of the authors made a case-control study to assess the risk factors and possible modes of transmission of hepatitis C virus (HCV) infection in patients without or with no history of drug abuse. METHODS: The study cases were selected from specialist gastroenterology outpatients at a university medical center in the southwestern United States. Fifty-eight of 477 HCV-positive patients who had no history of blood transfusion or drug-free history were enrolled as study cohorts. The control group consisted of 58 patients diagnosed with gastroesophageal reflux in the same outpatient setting, matched for age, race and gender with the study group. Patients were asked separately and the control group history and review of case records. Results There were a number of factors that were significantly associated with the spread of HCV infection, including history of tattoos, acupuncture history, history of sexually transmitted diseases, sex with drug injectors