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目的：本文在严格对照的背景下，研究石家庄地区GBS病人的空弯感染的情况。方法：分别采集了与GBS病人发病同期，相同居住环境的同一村庄及邻村健康人群做背景，对石家庄地区GBS病人的空弯感染的血清学情况做厂研究。共同时采集CSF及血清标本，对比两者抗体水平，以探讨CSF中Cj抗体的可能来源。且对病后不同病程的患者Cj空弯抗体滴度的变化规律进行了研究。结果GBS患者Cj近期感染率达80％左右，GBS病人发病同期，相同居住环境的同一村庄健康人群Cj感染达25．1％，GBS患者Cj抗体滴度自病后2周内逐渐增高，1月后呈下降趋势。患者血脑屏障通透性增高，CSF中检出Cj抗体，且CSF中CjIgG水平与血清抗体水平密切相关（r=O．88，P＜0．01）。结论：石家庄地区GBS病人的发病与Cj感染密切相关。
Objective: In this paper, in the context of strict control, the study of patients with GBS Shijiazhuang empty bend infection. Methods: The backgrounds of GBS patients in the same village and adjacent villages in the same period and with the same residential environment were collected respectively. The serological situation of empty bend infection in GBS patients in Shijiazhuang area was studied. CSF and serum samples were collected at the same time, comparing the antibody levels of the two to explore the possible source of Cj antibody in CSF. The changes of Ck empty bending antibody titer in patients with different duration of disease were studied. Results The recent infection rate of Cj was about 80% in GBS patients. In the same incidence of GBS patients, the incidence of Cj infection was 25.1% in the same village in the same residential environment. The titer of Cj antibody in GBS patients was gradually increased from 2 weeks after illness, After a downward trend. The permeability of blood-brain barrier increased, and Cj antibody was detected in CSF. The level of CjIgG in CSF was closely related to serum antibody level (r = 0.88, P <0.01). Conclusion: The incidence of GBS patients in Shijiazhuang is closely related to Cj infection.