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长期地服用异菸肼可能会发生维生素B缺乏的副作用。近来,曾发现在服用異菸肼过程中有40%的病人发生神经炎,而予服吡哆醇(Pyrido-xine)是很有效的。本文作者以实验论述:(1)一组实验之白鼠反复予服大剂量之異菸肼,而同时给予吡哆醇,则小鼠生长如常,另一对照组之小鼠,予服大量異菸肼而未给予吡哆醇,而引起小鼠胸線和睾丸的退化。这提示了可能是由于異菸肼在活体
Long-term use of isoniazid may occur side effects of vitamin B deficiency. Recently, it has been found that 40% of patients taking isoniazid develop neuritis, and taking pyridoxine (Pyrido-xine) is very effective. The author of the experiment to discuss: (1) a group of experimental rats repeatedly given large doses of isoniazid, while given pyridoxine, the mice grow as usual, another control group of mice, to be given a large number of different islets Hydrazine but did not give pyridoxine, causing mice chest and testicular degeneration. This suggests may be due to isoniazid in vivo