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研究富含单不饱和脂肪酸的橄榄油和富含多不饱和脂肪酸的鱼油对高血脂大鼠血脂水平及脂质过氧化的影响。方法：选用健康雄性Ｗｉｓｔａｒ大鼠共４０只，实验开始前按血清胆固醇和体重分为四组，正常对照组喂饲常备饲料，高脂对照组喂高脂饲料，橄榄油组和鱼油组除喂高脂饲料外，每日按每１００ｇ体重灌胃０．４ｍｌ相应的油脂，实验期为６周。高脂饲料含有５％猪油，１％胆固醇和０．２％的牛胆盐。每周称体重和记录进食量。实验末测定血清胆固醇（ＴＣ）、甘油三酯（ＴＧ）、高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）、血清丙二醛（ＭＤＡ）、红细胞超氧化物歧化酶（ＳＯＤ）活性。结果：１．橄榄油组和鱼油组大鼠的体重增长和进食量与高脂对照组相比无差异，但体重增长明显高于正常对照组。２．橄榄油组和鱼油组肝／体比值与高脂对照组比明显降低，而肾脏周围和睾丸周围的脂肪与体重的比值只有鱼油组与高脂对照组相比有明显的降低。３．橄榄油组与鱼油组ＴＣ和ＴＧ明显低于高脂对照组（Ｐ＜０．０５），并且鱼油较橄榄油效果好。（ＴＣ分别为９６３．０、６３１．９、１５３３．５ｍｇ／Ｌ；ＴＧ分别为８１７．６、６９８．３、１５８４．５ｍｇ／Ｌ）鱼油能显著提高ＨＤＬ－Ｃ的水平（Ｐ＜０．０５），橄榄?
To investigate the effects of monounsaturated fatty acid-rich olive oil and polyunsaturated fatty acid-rich fish oil on the level of serum lipids and lipid peroxidation in hyperlipidemic rats. Methods: A total of 40 healthy male Wistar rats were selected and divided into four groups according to serum cholesterol and body weight before the start of the experiment. The normal control group was fed with normal diet, the high-fat control group was fed with high fat diet, olive oil group and fish oil group High-fat diet, the daily per 100g body weight gavage 0.4ml corresponding fat, the experimental period of 6 weeks. High-fat diet contains 5% lard, 1% cholesterol and 0.2% bile salts. Weekly weighed and recorded food intake. At the end of the experiment, the levels of serum cholesterol, triglyceride, HDL-C, MDA and erythrocyte superoxide dismutase (SOD) were determined. Results: 1. There was no difference in body weight gain and food intake between the olive oil group and the fish oil group compared with the high fat control group, but the weight gain was significantly higher than that of the normal control group. 2. The liver / body ratio of olive oil group and fish oil group was significantly lower than that of high fat control group, while the ratio of fat to body weight around kidney and testis was only significantly lower in fish oil group than in high fat control group. 3. TC and TG in olive oil group and fish oil group were significantly lower than those in high-fat control group (P <0.05), and fish oil was better than olive oil. (TC respectively 963.0,631.9,1533.5mg / L; TG respectively 817.6,698.3,1584.5mg / L) fish oil can significantly increase the level of HDL-C (P <0.05 ), Olive?