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灭吐灵(Metoclopramide)是胃肠道兴奋药。它是氯苯酰胺衍生物,化学名称4-氨基-5氯-N-〔(2-二乙氨基)-乙基〕-2-甲氧苯酰胺盐酸盐。结构上与普鲁卡因酰胺相似,但无局部麻醉作用,亦无心脏选择作用。 灭吐灵经一次静注后,用于:(1)常规技术不易把插管通过幽门,用该药后可使插管顺利进入小肠,能有效地作空肠的活组织检查。(2)促进钡剂在胃排空和肠道输送。倘若排空延缓将增加胃或小肠的放射检查时间。(3)意外事故或妊娠急症,手术前应用可防止胃内容物误吸。
Metoclopramide is a gastrointestinal stimulant. It is a derivative of chlorobenzamide whose chemical name is 4-amino-5-chloro-N - [(2-diethylamino) -ethyl] -2-methoxybenzamide hydrochloride. Structure similar to procainamide, but no local anesthesia, nor cardiac selection. Metoclopramide once after intravenous injection, for: (1) conventional techniques difficult to intubation through the pylorus, with the drug can make the intubation smoothly enter the small intestine, can effectively for the jejunum biopsy. (2) to promote barium in the stomach emptying and intestinal delivery. A delay in emptying will increase the radiological examination of the stomach or small intestine. (3) Accident or pregnancy emergency, preoperative application can prevent aspiration of gastric contents.