反复发作是肾病综合征(NS)的特点,单纯性肾病综合征经首次类固醇治疗后复发者占60％,其中40～50％呈反复发作。本文将对复发性肾病综合征(RNS)的组织学变化、诱因、目前的治疗措施及其预后等方面的进展情况作一概述。 RNS的组织学变化原发性肾病综合征病理改变以微小病变型(Mc)居多;经类固醇治疗后能完全缓解者此亦占绝大多数,在儿童可达94％。因此,RNS病人仍以最初病理呈MC者为主,但随病程进展,其组织学将发生转化。在1964年,McGoven等即报道了MC中有组 Recurrent episodes are characteristic of the nephrotic syndrome (NS), which accounts for 60% of recurrent nephrotic syndromes after first steroid therapy, of which 40-50% recurrent. This article will outline the histological changes of recurrent nephrotic syndrome (RNS), the causes, the current treatment and prognosis of the progress made a summary. Histological changes of the nephrotic syndrome Nephrotic syndrome pathological changes to the smallest type of disease (Mc) mostly; steroid treatment can be completely relieved this also accounted for the vast majority, in children up to 94%. Therefore, patients with RNS is still the initial pathological MC was the main, but as the disease progresses, its histology will be transformed. In 1964, McGoven et al. Reported that there was a group in the MC