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目的 观察5%果糖注射液输注后对住院患者血糖水平的影响,评价其用于临床能量补充的有效性与安全性。方法采用随机盲法选取86例住院患者分为试验组和对照组。实验组40例,静脉滴注5%果糖注射液,对照组46例,静脉滴注5%葡萄糖注射液,连续3 d,比较两组的血糖、肝肾功能、血尿酸、血尿常规的变化。结果实验组给药后和给药后2 h血糖均无明显变化,对照组给药后血糖出现一过性升高(P<0.01),2 h后恢复到给药前水平。5%果糖注射液对肝、肾功能、血尿液等指标无影响。结论输注5%果糖注射液后血糖水平波动明显小于5%葡萄糖,5%果糖注射液用于临床患者机体能量补充安全有效。
Objective To observe the effect of 5% fructose injection on blood glucose level in hospitalized patients and evaluate its effectiveness and safety for clinical energy supplementation. Methods A total of 86 hospitalized patients were randomly divided into experimental group and control group. The experiment group consisted of 40 cases with 5% fructose injection and 46 cases with control group. The rats in the control group were treated with 5% dextrose injection for 3 consecutive days. The changes of blood sugar, liver and kidney function, serum uric acid and hematuria were compared between the two groups. Results There were no significant changes of blood glucose in experimental group and 2 h after administration, while the control group had a transient increase in blood glucose after administration (P <0.01), and returned to the pre-administration level after 2 h. 5% fructose injection of liver, kidney function, blood and urine and other indicators had no effect. Conclusion The infusion of 5% fructose injection blood glucose levels were significantly less than 5% glucose, 5% fructose injection for clinical patients with energy supplement is safe and effective.