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本文对支气管痉挛状态大鼠及支气管哮喘病人进行了研究,以探讨肠道吸附疗法在支气管哮喘综合治疗中的意义及其作用机制.结果表明:治疗组大鼠外呼吸功能明量好转,与实验组相比有统计学差异(P<0.05);血浆中组胺、循环免疫复合物及IgE含量均较实验组明显减少(P<0.05)。在临床观察中发现,观察组病人一般症状明显好转,外呼吸功能改善显著,与对照组相比其肺活量及肺活量与每秒呼气量之比增加,均有统计学意义(P<0.05)。同时观察到观察组病人外周血中T-细胞、B-细胞数也明显增多。结果提示肠道吸附疗法在支气管哮喘的治疗中具有减低生物活性物质、增强免疫功能、改善外呼吸功能的作用。
In this paper, bronchospasm rats and bronchial asthma patients were studied in order to explore the significance of intestinal absorption therapy in the comprehensive treatment of bronchial asthma and its mechanism of action.The results showed that: the treatment group, (P <0.05). The contents of histamine, circulating immune complex and IgE in plasma were significantly lower than those in experimental group (P <0.05). The clinical observation showed that the general symptoms of the observation group were significantly improved and the external respiration function improved significantly. Compared with the control group, the vital capacity and the ratio of vital capacity to exhaled volume per second increased significantly (all P <0.05). In the meantime, the number of T-cells and B-cells in the peripheral blood of patients in the observation group also increased significantly. The results suggest that intestinal absorption therapy in the treatment of bronchial asthma with bioactive substances to reduce, enhance immune function, improve the role of respiratory function.