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目前关于人体内朗格汉斯细胞 (LC)移行的资料非常有限 ,为进一步定量研究肿瘤坏死因子 (TNF) -α刺激人LC移行的能力 ,作者研究了TNF-α对CD1a+和HLA -DR+表皮细胞的密度及对LC形态的影响。TNF-α引起表皮CD1a+LC密度降低 :给 1~ 9号 (第一组 )、
At present there is very limited information on the migration of Langerhans cells (LC) in humans. To further quantify the ability of tumor necrosis factor (TNF) -α to stimulate human LC migration, we investigated the effect of TNF-α on CD1a + and HLA-DR + Density of epidermal cells and their effect on LC morphology. TNF-α causes a decrease in epidermal CD1a + LC density: from 1 to 9 (group 1),