以硝酸胍、丙二酸二乙酯和糖精为起始原料,经5步反应合成了苯磺酰脲类除草剂氟嘧磺隆。所得产物纯度为99%,总收率为31·2%。且该路线具有原料易得、反应条件温和、操作简单等优点。 Benzenesulfonylurea herbicides, forsythosulfuron, were synthesized by five steps using guanidine nitrate, diethyl malonate and saccharin as starting materials. The resulting product had a purity of 99% and a total yield of 31.2%. And the route has the advantages of raw materials, mild reaction conditions, easy operation and so on.