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目的探讨CA125、AFP、CEA血清表达水平对卵巢癌诊断的价值。方法:采用酶联免疫法检测健康人群、良性肿瘤及卵巢癌患者血清中CA125、AFP、CEA表达水平,并进行比较分析。结果:卵巢癌患者血清CA125表达(375.2±350)u/ml、CEA表达(9.6±8.6)ng/ml水平明显高于健康人群、良性肿瘤患者(P<0.05);AFP表达无显著性差异(P>0.05);结论:CA125作为卵巢癌敏感指标与CEA、AFP联合检测对卵巢肿瘤患者的诊断、治疗及预后观测具有重要价值。
Objective To investigate the serum levels of CA125, AFP and CEA in the diagnosis of ovarian cancer. Methods: The serum levels of CA125, AFP and CEA in healthy people, benign tumors and ovarian cancer patients were detected by enzyme-linked immunosorbent assay and compared. Results: The serum level of CA125 in patients with ovarian cancer was significantly higher than that in healthy people (benign tumor) (375.2 ± 350) u / ml and CEA (9.6 ± 8.6) ng / ml P> 0.05). CONCLUSION: Combined detection of CA125 as a sensitive indicator of ovarian cancer and CEA and AFP is of great value in the diagnosis, treatment and prognosis of ovarian cancer patients.