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目的观察尿毒症透析及非透析患者血浆ＩＬ－１３水平的变化。方法采用ＥＬＩＳＡ法检破慢性肾功能衰竭尿毒症患者血浆ＩＬ－１３含量。结果尿毒症患者血浆中ＩＬ－１３水平较对照组明显升高（Ｐ＜０．０１），透析组与非透析组ＩＬ－１３水平的差异无统计学意义，且与血清尿素氮和肌研无明显相关性。结论ＩＬ－１３作为炎症抑制因子在治疗尿毒症患者有重要意义。
Objective To investigate the changes of plasma IL-13 levels in uremic patients with and without dialysis. Methods The plasma IL-13 levels in patients with chronic renal failure and uremia were detected by ELISA. Results The plasma level of IL-13 in uremia patients was significantly higher than that in control group (P <0.01). There was no significant difference in IL-13 levels between dialysis group and non-dialysis group Correlation. Conclusion IL-13 as an inhibitor of inflammation in the treatment of uremic patients have important significance.