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2型糖尿病作为缺血性脑梗死主要的独立危险因素,同时也是临床可干预的危险因素,2型糖尿病的患者发生脑梗死的风险比非2型糖尿病的患者高出5~10倍。2型糖尿病并发脑梗死的发病机制主要与糖尿病代谢紊乱造成微血管、大血管及血液流变和抗凝纤溶系统异常有关[1]146,糖尿病引起的动脉硬化是脑血管病的病理基础之一。
Type 2 diabetes mellitus is a major independent risk factor for ischemic stroke and is also a clinically relevant risk factor. Patients with type 2 diabetes have a 5 to 10-fold greater risk of developing cerebral infarction than non-type 2 diabetes. The pathogenesis of type 2 diabetes mellitus complicated with cerebral infarction is mainly related to the abnormalities of microvascular, macrovascular and blood rheology and anticoagulant fibrinolytic system caused by the disorder of diabetes mellitus.146 Diabetes-induced arteriosclerosis is one of the pathological basis of cerebrovascular disease .