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用氮芥、长春新碱、强的松和甲基苄肼(MOPP)联合治疗(同时用或不用放疗)何杰金病后急性非淋巴细胞性白血病的发生率令人担心,因而有些临床医师提出用交替给药方案。本文报告马萨诸塞州总医院在15年期间这一并发症的情况。经活检证实的何杰金病共408例,年龄≤60岁,均进行了何杰金病治疗,其中发现8例急性非淋巴细胞性白血病,1例并发非何杰金淋巴瘤,急性非淋巴细胞性白血病12年的保险统计的危险率(actuarial
The incidence of acute non-lymphocytic leukemia following Hodgkin’s disease was associated with the combination of mechlorethamine, vincristine, prednisone and procarbazine (MOPP) with or without radiotherapy and some clinicians Proposed alternate drug delivery program. This article reports the complication of the Massachusetts General Hospital over a 15-year period. Hodgkin’s disease confirmed by biopsy of a total of 408 cases, ≤ 60 years of age, were treated Hodgkin’s disease, which found 8 cases of acute non-lymphocytic leukemia, 1 case complicated by non-Hodgkin’s lymphoma, acute non-lymph 12-year risk of CLL in actuarial