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目的 探讨不同类型胃息肉与幽门螺杆菌感染的关系。方法 经胃镜活检及病理诊断胃息肉106例,内镜下摘除的胃息肉作HE染色,判定胃息肉组织学类型及炎症反应程度。同时在胃窦部取材2～3块,分别作快速尿毒酶试验及美蓝染色,以检测Hp感染率,两者均阳性判为Hp感染。结果 106例胃息肉Hp总检出率为65.1％。胃息肉以增生息肉多见,共76例,占71.7％,腺癌性息肉30例,占28.3％。Hp感染率在增生性息肉中为73.7％(56/76),显著高于腺癌性息肉43.1％(13/30)(P<0.01)。活动性炎症在增生性息肉中为55.3％(42/76),显著高于腺瘤性息肉 0％(9/30)(P>0.05)。结论 增生性息肉的发生可能与Hp感染有关,这可能与Hp引起胃粘膜活动性炎症反应有关。
Objective To investigate the relationship between different types of gastric polyps and Helicobacter pylori infection. Methods Gastric endoscopic biopsy and pathological diagnosis of 106 cases of gastric polyps, endoscopic removal of gastric polyps for HE staining, determine the type of gastric polyps and inflammation. At the same time, 2 to 3 pieces of antrum were taken from the gastric antrum for rapid uremic enzyme assay and methylene blue staining to detect the Hp infection rate. Both were positive for Hp infection. Results The total detection rate of Hp in 106 cases of gastric polyps was 65.1%. Gastric polyps were more common in hyperplastic polyps, totaling 76 cases, accounting for 71.7%, and adenocarcinoma polyps in 30 cases, accounting for 28.3%. Hp infection rate was 73.7% (56/76) in hyperplastic polyps, which was significantly higher than that of adenocarcinoma polyps (43.1%, 13/30) (P<0.01). Active inflammation was 55.3% (42/76) in hyperplastic polyps, which was significantly higher than 0% (9/30) in adenomatous polyps (P>0.05). Conclusion The occurrence of proliferative polyps may be related to Hp infection, which may be related to the active inflammatory response of gastric mucosa caused by Hp.