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目的探讨腹腔镜下行结肠癌前哨淋巴结活检的可行性及临床意义。方法选取本院2012年1月-2013年7月间收治的结肠癌患者60例,一组40例采用开放染色前哨淋巴结活检,另一组20例采用腹腔镜下前哨淋巴结活检,在肿瘤的上下左右四个方向,距其边缘0.5-1.0cm处的各点黏膜下,注射1%异硫蓝(美国Sigma公司)0.25ml,一共1.0ml。比较两组SLN检出率和术后并发症。结果两组SLN检出率、NSLN检出率及SLN检测准确率、特异性、假阴性率、阳性及阴性预测值均无显著性差异(P>0.05)。结论腔镜下SLNB与传统SLNB可达到相似的临床效果,可作为结肠癌SLN活检技术进行推广应用。
Objective To investigate the feasibility and clinical significance of laparoscopic sentinel lymph node biopsy of colon cancer. Methods Sixty patients with colon cancer who were treated in our hospital from January 2012 to July 2013 were selected. One group of 40 patients underwent open stained sentinel lymph node biopsy and the other 20 patients underwent laparoscopic sentinel lymph node biopsy. About four directions, from the edge of 0.5-1.0cm at the submucosal point, injection of 1% isosulfan (Sigma, USA) 0.25ml, a total of 1.0ml. SLN detection rate and postoperative complications were compared between the two groups. Results The SLN detection rate, NSLN detection rate and SLN detection accuracy, specificity, false negative rate, positive and negative predictive value had no significant difference (P> 0.05). Conclusions Endoscopic SLNB and traditional SLNB can achieve similar clinical effect, which can be used as SLN biopsy technology for colon cancer.