目的分析医院抗菌药物不良反应(ADR)相关因素,促进合理用药。方法对医院2013年收集上报的81例抗菌药物ADR进行回顾性统计分析。结果 ADR 81例,喹诺酮类引起ADR最多(46.91%),给药途径以静脉滴注引起ADR最常见(91.36%),临床表现以皮肤及其附件损害居多(69.14%)。结论抗菌药物ADR发生主要与患者年龄、给药途径、给药频次相关。应重视抗菌药物ADR报告与监测工作,保障用药安全。 Objective To analyze the related factors of adverse drug reaction (ADR) in hospital and to promote rational drug use. Methods A retrospective statistical analysis of 81 cases of ADR collected and reported by the hospital in 2013 was performed. Results 81 cases of ADR were the most common cause of ADR (46.91%). Intravenous infusion of ADR caused the most common ADR (91.36%). The clinical manifestations were mostly skin and its accessories (69.14%). Conclusion The occurrence of antimicrobial agents ADR mainly associated with patient age, route of administration, frequency of administration. Should pay attention to the ADR report and monitoring of antimicrobial agents, to ensure drug safety.