硝硫氰胺是抗血吸虫病的一种新药物。本文进一步研究该药物对实验性日本血吸虫病的预防和治疗的作用。 实验动物在感染血吸虫尾蚴前后,即使口服500mg/kg/天×2或4天的硝硫氰胺,血吸虫组比对照组仅减少32.3～59％。药物对童虫几乎无作用,而对成虫则有明显的疗效。病鼠一次口服硝硫氰胺40mg/kg,停药后1～8天的肝移率达93.6～100％。各实验治疗组的减虫率为74～100％,但此疗效的高低与剂量和疗程有关。 Nitrocyanamine is a new drug against schistosomiasis. This article further studies the role of the drug in the prevention and treatment of experimental Japanese schistosomiasis. Before and after infection with schistosome cercariae, the experimental animals showed a reduction of only 32.3% -59% in the schistosomiasis group compared with the control group, even though oral administration of 500 mg / kg / day x 2 or 4 days of nitinamide. Drugs have almost no effect on the wolves, while adults have a significant effect. Sick mice once oral nitrofurazone 40mg / kg, 1 to 8 days after stopping the liver transfer rate of 93.6 to 100%. The worm reduction rate of each experimental group was 74 ~ 100%, but the level of efficacy was related to the dosage and course of treatment.