论文部分内容阅读
贯叶金丝桃(Hypericum perforatum L.)作为民间草药用于治疗神经疾病、创伤、烧伤、尿路感染已有几个世纪。现代研究证实了其抗菌、抗病毒、抗炎、镇静以及脑化学修饰等方面的活性。新近的研究发现,贯叶金丝桃的两种主要活性成分金丝桃素和假金丝桃素具有很强的抑制艾滋病毒作用,且毒性很低。有报道说动物用了这种植物,会产生光过敏反应,所以美国食品及药物管理局对贯叶金丝桃的所有植物制剂的安全性尚未认可。不过,对人的毒性作用至今还未见报道。
Hypericum perforatum L. has been used as a folk herb for centuries in the treatment of neurological diseases, trauma, burns, and urinary tract infections. Modern studies have confirmed its activity in terms of antibacterial, antiviral, anti-inflammatory, sedative, and brain chemical modifications. Recent studies have found that hypericin and pseudo hypericin, the two main active ingredients of St. John’s Wort, have a strong inhibitory effect on HIV and have low toxicity. It has been reported that animal use of this plant will produce a photoallergic reaction, so the US Food and Drug Administration has not recognized the safety of all plant preparations of Hypericum. However, no toxic effects on humans have been reported so far.