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目的探讨弹力纤维瘤的临床及病理学特征。方法回顾性分析22例弹力纤维瘤的临床资料、组织学形态、免疫组化及弹力纤维染色。结果弹力纤维瘤好发于肩胛骨下部;肿物由大量胶原纤维及异形弹力纤维组成。弹力纤维呈串珠状、锯齿状排列或呈球状、碎屑状,其间见成熟的脂肪组织;免疫组化vimentin(+),SMA、desmin、S-100和p53(-);弹力纤维染色(+)。结论弹力纤维瘤为弹力纤维性肿瘤样病变,结合其好发部位、组织病理学特点、免疫组化标记和弹力纤维特殊染色可做出准确诊断。
Objective To investigate the clinical and pathological features of elastic fibroids. Methods A retrospective analysis of 22 cases of biliary fibroids clinical data, histological morphology, immunohistochemistry and elastic fiber staining. Results of elastic fibroids occur in the lower part of the scapula; mass by a large number of collagen fibers and shaped elastic fibers. Elastic fibers were beaded, jagged or globular and crumbed with mature adipose tissue. Immunohistochemistry showed that vimentin (+), SMA, desmin, S-100 and p53 (- ). Conclusion Elastic fibroma is an elastic fibrous tumor-like lesion, which can be accurately diagnosed by combining its predilection sites, histopathological features, immunohistochemical markers and special staining of elastic fibers.