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目的:观察能谱CT在甲状腺良恶性结节鉴别中的应用效果。方法:选取梅州市人民医院2014年7月-2015年1月接收且经手术病理证实的80例甲状腺结节患者为研究对象,其中40例良性结节患者为组1,另40例恶性结节患者为组2。另以同时期40例甲状腺正常者为参照对象,设为对照组。比较3组能谱CT不同期相的碘浓度值、碘浓度比、能谱衰减曲线斜率。结果:对照组平扫期、动脉期与静脉期的相碘浓度分别为(20.11±6.74)100μg/m L、(25.88±10.03)100μg/m L、(40.01±7.97)100μg/m L,能谱衰减曲线斜率分别为(-1.27±0.61)%、(-2.35±0.79)%、(-2.93±0.64)%,组1平扫期、动脉期与静脉期的相碘浓度分别为(10.70±4.35)100μg/m L、(16.51±6.67)100μg/m L、(28.97±11.34)100μg/m L,能谱衰减曲线斜率分别为(-0.79±0.37)%、(-1.30±0.48)%、(-1.93±0.56)%;组2平扫期、动脉期与静脉期的相碘浓度分别为(6.23±3.07)100μg/m L、(7.79±4.72)100μg/m L、(17.03±7.95)100μg/m L,能谱衰减曲线斜率分别为(-0.45±0.32)%、(-0.79±0.35)%、(-1.16±0.39)%。3组动脉期、静脉期的碘浓度值和能谱衰减曲线斜率比较,差异具有统计学意义(P<0.05)。对照组动脉期、静脉期的碘浓度比分别为(0.70±0.43)%、(1.08±0.27)%,组1动脉期、静脉期的碘浓度比分别为(0.33±0.17)%、(0.70±0.19)%,组2动脉期、静脉期的碘浓度比分别为(0.25±0.18)%、(0.54±0.15)%;3组静脉期的碘浓度比比较,差异具有统计学意义(P<0.05)。结论:能谱CT鉴别甲状腺良恶性结节的应用效果良好。
Objective: To observe the effect of energy spectrum CT in differentiating benign and malignant thyroid nodules. Methods: 80 cases of thyroid nodules confirmed by pathology of our hospital from July 2014 to January 2015 in Meizhou People’s Hospital were enrolled. Among them, 40 cases of benign nodules were group 1 and 40 cases of malignant nodules Patient is Group 2. The other 40 cases of thyroid during the same period as a reference object, as the control group. The iodine concentration, the iodine concentration ratio and the slope of the energy spectrum decay curve were compared between the three groups. Results: In the control group, phase iodine concentrations in arterial phase and venous phase were (20.11 ± 6.74) 100μg / m L, (25.88 ± 10.03) 100μg / m L, (40.01 ± 7.97) 100μg / m L (-1.27 ± 0.61)%, (-2.35 ± 0.79)% and (-2.93 ± 0.64)%, respectively. During group 1, the phase iodine concentrations in arterial phase and venous phase were (10.70 ± 4.35), the slope of the spectrum decay curve was (-0.79 ± 0.37)%, (-1.30 ± 0.48)%, (-1.93 ± 0.56)% respectively. During phase 2, the iodine concentrations in arterial phase and venous phase were (6.23 ± 3.07) 100μg / m L, (7.79 ± 4.72) 100μg / m L and (17.03 ± 7.95) (-0.45 ± 0.32)%, (-0.79 ± 0.35)% and (-1.16 ± 0.39)%, respectively. The difference of iodine concentration between the arterial phase and venous phase in three groups was statistically significant (P <0.05). The ratio of iodine in arterial phase and venous phase were (0.70 ± 0.43)% and (1.08 ± 0.27)% respectively in control group and (0.33 ± 0.17)% and (0.70 ± 0.19)%, respectively. The iodine concentrations in arterial phase and venous phase in group 2 were (0.25 ± 0.18)% and (0.54 ± 0.15)%, respectively. ). Conclusion: The application of spectrum CT in differentiating benign and malignant thyroid nodules has good effect.