解答:创伤性毛细血管渗漏综合征(trauma-induced capillary leak syndrome,TICS)手术后或各种严重创伤后继发的毛细血管内皮损伤。通透性增加,血管内血浆蛋白等大分子物质渗漏至组织间隙,出现低蛋白血症、有效循环血量不足,导致低血容量休克、急性肾缺血等临床综合征,严重时可发生多器官功能衰竭。与一般的毛细血管渗漏综合征不同,TICS分为出血未控制期、渗漏期和血管再充盈期(恢复期),三个时期发病机制和临床表现各不同,治疗原则有时截然相反。目前诊断TICS主要根 ANSWER: Trauma-induced capillary leak syndrome (TICS) Post-surgical or various capillary endothelial damage secondary to trauma. Increased permeability, intravascular plasma proteins and other macromolecular substances leakage to the tissue gap, hypoproteinemia, lack of effective circulating blood volume, leading to hypovolemic shock, acute renal ischemia and other clinical syndromes, may occur in severe cases Multiple organ failure. Different from the general capillary leak syndrome, TICS is divided into uncontrolled bleeding, leaking period and vascular reperfusion (recovery period). The pathogenesis and clinical manifestations of the three periods are different, and the treatment principle is sometimes opposite. The main root of TICS is currently diagnosed