自从乙烯塑料薄膜隔离器作为无菌动物的饲育装置开发以来,已经历了二十多年。乙烯塑料薄膜隔离器(以下简称隔离器)使用简便,最近也被广用于裸鼠和SPF动物的饲育中。可是在隔离器中饲育动物时,易因停电造成送风障碍而导致动物死亡,并且,隔离器内一旦饲育SPF动物,其中氨气浓度也易显著提高。因此,作者等以过去在实验动物中央研究所进行实验的一部分和在本设施进行的实验数据为基础,对隔离器的饲育 It has been more than two decades since the development of ethylene plastic film separators as breeding devices for sterile animals. Ethylene plastic film isolators (hereinafter referred to as isolators) are easy to use and have recently been widely used in the breeding of nude mice and SPF animals. However, when animals are bred in the isolator, it is easy to cause the animal to die due to wind power failure caused by the power outage, and once the SPF animal is reared in the isolator, the concentration of ammonia gas is also likely to increase significantly. Therefore, the authors, etc., based on the part of the experiments conducted in the Central Research Institute of Experimental Animals and the experimental data performed in the facility, the rearing of the isolator.