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3 临床药代动力学研究3.1 研究目的和一般要求 研究的目的是了解新药在人体内的吸收、分布与消除的规律 ,为制定合理的给药方案提供依据。一般要求作单剂给药的药代动力学。应尽量采用灵敏、专一的检测技术测定药物的血 (或尿 )浓度。按给药途径 ,选择推荐临床治疗用的剂量
3 Clinical pharmacokinetics 3.1 The purpose of the study and general requirements The purpose of the study is to understand the absorption of new drugs in the body, distribution and elimination of the law, to provide a reasonable basis for the dosing program. General requirements for pharmacokinetics for single-dose administration. Should try to use sensitive, specific detection technology to determine the drug’s blood (or urine) concentration. According to the route of administration, choose the recommended dosage for clinical treatment