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用SPECT检查骨缺损修复效果。40只新西兰白兔均于两侧桡骨干造成15cm缺损后分成4组,A组植入25mg骨形态发生蛋白(BMP)与纤维蛋白的复合物;B组植入25mgBMP;C组单纯植入纤维蛋白;D组不植入任何材料。术后不同时间进行骨骼显像,同时进行放射学和组织学检查。结果术后1周发现再生性骨盐沉积活动,以A组最为活跃,B组其次,所揭示规律与组织学和放射学检查结果吻合。因此,SPECT和常规检查方法联合应用,可以更早、更全面地评价骨缺损修复的效果。
SPECT examination of bone defect repair effect. Forty New Zealand white rabbits were divided into 4 groups after the defect of 15cm on both sides of the radial bone. Group A was implanted with 25mg bone morphogenetic protein (BMP) and fibrin complex; group B was implanted with 25mg BMP; Into fibrin; D group is not implanted with any material. Bone imaging was performed at different times after surgery, and radiology and histology were performed simultaneously. Results One week after operation, regenerative bone salt deposition was found in group A, the most active group A, followed by group B. The revealed regularities were consistent with histological and radiological findings. Therefore, the combination of SPECT and routine examination can evaluate the effect of bone defect repair earlier and more comprehensively.