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目的探讨儿童全身炎症反应综合征与血清降钙素原(PCT)的相关性。方法 80例全身炎症反应综合征患儿作为实验组,其中细菌性感染53例(细菌感染组),非细菌性感染27例(非细菌感染组);80例健康儿童作为对照组,对各组血清PCT、C反应蛋白(CRP)以及白细胞介素-6(IL-6)水平进行检测,并进行比较。结果实验组患儿入院第1、5天血清IL-6、PCT以及CRP水平均显著高于对照组(P<0.05);入院第1、5天细菌感染组患儿血清PCT水平均显著高于非细菌感染组(P<0.05)。结论 PCT可较好地区分患儿的致病因素,对临床诊断细菌性感染所致的全身炎症反应综合征有较高的临床意义。
Objective To investigate the correlation between systemic inflammatory response syndrome and serum procalcitonin (PCT) in children. Methods 80 cases of systemic inflammatory response syndrome children as experimental group, of which 53 cases of bacterial infection (bacterial infection group), non-bacterial infection in 27 cases (non-bacterial infection group); 80 healthy children as a control group, Serum PCT, C-reactive protein (CRP) and interleukin-6 (IL-6) levels were detected and compared. Results The serum levels of IL-6, PCT and CRP in the experimental group were significantly higher than those in the control group on the first and fifth day after admission (P <0.05). The PCT levels in the bacterial infection group were significantly higher than those in the control group Non-bacterial infection group (P <0.05). Conclusion PCT can better distinguish the risk factors of children, and has a high clinical significance for clinical diagnosis of systemic inflammatory response syndrome caused by bacterial infection.