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自1992年2月~1996年10月,我科使用它莫西芬治疗70例特发性少精症。在三个月为一疗程的治疗后,78.6%的精子数量有一定程度提高,但是各人的差异较大,38.2%的精子数量提高到20×106/ml以上,虽然它莫西芬能提高精子的数量,但对精液的其它参数,如pH、精子活率、活力及液化时间均无明显影响。本文仅有7例原精子质量较好的病人经治疗后使其妻受孕。治疗前后的性激素检查发现,FSH、LH和T有明显的提高,而PRL和E2变化甚微。病人在治疗期间没有明显副作用发生。
From February 1992 to October 1996, our department used tamoxifen to treat 70 cases of idiopathic oligozoospermia. After three months of treatment, the number of sperm in 78.6% increased to a certain degree, but the differences among them were quite large, and the number of sperm in 38.2% increased to more than 20 × 106 / ml, although it was not Cephen could increase the number of sperm, but had no significant effect on other parameters of sperm such as pH, sperm motility, vitality and liquefaction time. In this paper, only 7 patients with better spermatozoa were pregnant to confer their wives. Hormone test before and after treatment found that FSH, LH and T increased significantly, while little changes in PRL and E2. The patient had no significant side effects during treatment.