特发性肺间质纤维化（IPF）临床虽不罕见，但治疗仍较棘手。我科1985年以来收治12例，认为早期诊断，及时洽疗，部分病例可得以延缓生命。临床资料本组12例，慢性起病9例，亚急性起病3例；男性8例，女性4例。年龄19～72岁。7例行纤支镜肺活检，1例尸检，组织学改变均符合IPF表 Although idiopathic pulmonary interstitial fibrosis (IPF) is not uncommon, but the treatment is still more difficult. In our department, 12 cases were treated since 1985, which means early diagnosis and prompt treatment can delay the life of some patients. Clinical data The group of 12 cases, 9 cases of chronic onset, subacute onset in 3 cases; 8 males and 4 females. Age 19 ~ 72 years old. 7 cases of bronchoscopy lung biopsy, an autopsy, histological changes are in line with the IPF table