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目的 研究Ortho KCL矫正治疗近视病例中角膜OK环 (角膜旁中心上皮下棕色沉淀环 )发生率及其影响因素。方法 对在本中心验配Ortho KCL以及其他机构验配Ortho KCL 1年以上病例观察角膜OK环发生率 ,并探讨屈光度、镜片使用时间、CL降度设计、配适状态、角膜内皮细胞改变、其他角结膜并发症等因素与角膜OK环发生的关系。结果 本中心验配Ortho KCL采用夜戴 /弹性配戴和日戴的不同方式 ,戴镜 1年以上 2 68例 5 3 2眼中无一眼出现角膜OK环。而其他机构全部采用夜戴方式 ,戴镜 1年以上 2 5 8例 5 1 5眼中 89眼发现角膜环 ,占 1 7 3 %。a组 (有OK环 )与b组(其他机构 ,无OK环 )对比分析结果显示 ,a组戴镜时间 1 5年± 0 7年 ,b组 1 3年± 0 6年 (P =0 0 1 4)。a组近视球镜度 6 3 2± 1 74D ,b组 4 2 1D± 1 85D (P <0 0 1 )。裸眼角膜平坦K值a组43 76D± 1 2 4,b组 43 2 7D± 1 3 9D (P <0 0 5 ) ,Ortho KCL降度设计 ,a组平均减 6 2 5D± 2 0 5D ,b组平均减 4 1 8D± 1 2 3D (P <0 0 1 )。a组 70 %以上显示配适状态不良 ,65 %以上角膜不良变形或呈假性圆锥角膜改变。其它角结膜并发症a组高于b组。与同年龄组健康非戴镜眼比较 ,两组角膜内皮细胞密度显著降低 ,内皮细胞变异系数明显增高 ,但两?
Objective To investigate the incidence and influential factors of OK ring (corneal central subepithelial brown precipitate ring) in Ortho KCL correction treatment of myopia. Methods The incidence of corneal OK ring in Ortho KCL and other institutions with Ortho KCL matched for more than 1 year was observed and the refraction, lens usage time, CL lowering design, status of adaptation, changes of corneal endothelial cells and other Corneal conjunctival complications and other factors and the relationship between OK ring. Results The center fitted Ortho KCL with night wear / elastic wear and daily wear of different ways, wearing glasses for more than 1 year 2 68 cases 5 3 2 eyes without corneal OK ring. The other agencies all use the night wear method, wearing glasses for more than 1 year 258 cases 5 1 5 89 eyes found corneal ring, accounting for 17.3%. The results of comparative analysis of group a (with OK ring) and group b (other institutions without OK ring) showed that the wearing time of group a was 15 ± 0 and the group b was 13 ± 6 years (P = 0 0 1 4). Myopia in group a was 6 3 2 ± 1 74D, group 4 4 1D ± 1 85D (P 0 01). The average corneal flat K value in a group was 43 76D ± 1 2 4, in group b 43 2 7D ± 1 3 9D (P 0 05), and Ortho KCL was designed for degeneration. The mean reduction in group a was 6 2 5D ± 2 0 5D, b The group averaged 4 1 8D ± 1 2 3D (P <0 0 1). More than 70% of a group showed poor fit status, more than 65% corneal deformity or pseudo-keratoconus change. Other keratoconjunctival complications were higher in group a than in group b. Compared with healthy non-wearing glasses in the same age group, the density of corneal endothelial cells in both groups decreased significantly and the coefficient of variation of endothelial cells increased significantly,