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目的:研究挂金灯活性部位对佐剂诱导性大鼠类风湿关节炎症的影响。方法:采用大鼠足趾注射完全费氏佐剂复制大鼠类风湿关节炎模型,观察挂金灯活性部位对大鼠类风湿关节炎症的影响。结果:挂金灯活性部位高、中、低浓度组对大鼠体质量的影响相对都较轻,以高剂量组治疗效果明显;挂金灯活性部位高、中、低剂量组均可以减轻费氏完全佐剂引发的大鼠足趾肿胀,其中高剂量组抑制作用最强。结论:挂金灯活性部位对AA大鼠有明显的抗炎消肿作用,能减轻或减缓炎性反应,具有减轻关节肿胀、不良反应低的特点。
Objective: To study the effect of the active part of hanging lamp on the rheumatoid arthritis induced by adjuvant in rats. Methods: Rat model of rheumatoid arthritis was induced by complete Freund’s adjuvant injected into the toe of rats, and the effect of active site of hanging lamp on the rheumatoid arthritis of rats was observed. Results: The activity of high, medium and low concentration groups of active gold lamp were relatively lower than that of high-dose group, and the treatment effect was obvious in high-dose group. Complete adjuvant-induced rat toe swelling, of which high-dose group, the strongest inhibitory effect. CONCLUSION: The active part of hanging lamp has obvious anti-inflammation and detumescence effect on AA rats, which can reduce or slow the inflammatory reaction, relieve the swelling of joint and low adverse reaction.