原发性扩张型心肌病(DCM)心腔内常发生血栓,并引起栓塞并发症,一般认为由于心输出量减少,心腔内血流缓慢所致。原发性DCM是否也因为血液流变学异常,促使心腔内血栓形成,加重组织缺血缺氧尚不清楚,故作者研究其血液流变学的变化。方法:病例组原发性DCM60例,多普勒超声心动图确定诊断。凡有严重的心瓣膜疾病、高血压、急性心肌炎、严重的冠状动脉疾病、动脉闭塞性疾病、糖尿病、高脂血症、吸烟、使用了影响血液流变学药物者均不纳入。对照组25例,按性别、年龄配对,均无吸烟、肿瘤、炎症及代谢性疾病。取静脉血测定纤维蛋白原、血浆粘度,红细胞压积、红细胞聚集性、全血粘弹性指标包括低、中、高切变率下粘性分量,弹性分量,调整红细胞压积在 Thrombosis often occurs in the heart cavity of primary dilated cardiomyopathy (DCM) and causes embolic complications. It is generally believed that due to a decrease in cardiac output and a slow intracardiac blood flow. Whether the primary DCM is also due to abnormal blood rheology, to promote intracardiac thrombosis, increased tissue ischemia and hypoxia is not clear, so the authors study the changes in hemorheology. Methods: 60 cases of primary DCM were diagnosed by Doppler echocardiography. Anyone who has severe heart valve disease, high blood pressure, acute myocarditis, severe coronary artery disease, arterial occlusive disease, diabetes, hyperlipidemia, smoking, and medication that affects hemorrheology is not included. Control group of 25 cases, by sex, age matched, no smoking, cancer, inflammation and metabolic diseases. Venous blood was taken for determination of fibrinogen, plasma viscosity, hematocrit, erythrocyte aggregation, and whole blood viscoelasticity indicators including viscous components at low, medium, and high shear rates, elastic components, adjusting hematocrit at