目的 :观察康泉、胃复安控制化疗引起的恶心、呕吐的作用及其毒副作用。方法 :将 50例恶性肿瘤病人随机分成康泉组、胃复安组进行化疗。结果 :康泉组及胃复安组平均恶心的控制率(CR+PR)分别为 88.5%、65.5% ,有统计学差异 ;平均止吐率分别为 93.5%、67.3% ,有统计学差异 ,康泉的副作用小。结论 :康泉是一种强有力的胃肠反应抑制剂 ,作用时间长 ,毒副作用轻微 Objective: To observe the effects of Kangquan and Metoclopramide on controlling nausea and vomiting caused by chemotherapy and their toxic and side effects. Methods: 50 patients with malignant tumors were randomly divided into Kangquan group and Weifu’an group for chemotherapy. Results: The mean control rate (CR+PR) of the Kangquan group and the metoclopramide group was 88.5% and 65.5%, respectively, with statistical differences; the average antiemetic rates were 93.5% and 67.3%, respectively, with statistical differences. Kangquan’s side effects are small. Conclusion: Kangquan is a potent gastro-intestinal response inhibitor with long duration of action and slight side effects