超声检测缺血性脑卒中/短暂性脑缺血发作患者颈动脉粥样硬化与冠状动脉粥样硬化的相关性研究

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目的探讨超声检测缺血性脑卒中/短暂性脑缺血发作患者颈动脉粥样硬化与冠状动脉粥样硬化的相关性。方法选取我院2014年4月~2016年3月收治的缺血性脑卒中/短暂性脑缺血发作患者122例为观察组,其中冠状动脉粥样硬化61例为A组,另选取120例同期健康体检者为对照组,均行颈动脉超声检测,观察比较颈动脉斑块发生率及斑块类型,观察对比A组不同病变支数间斑块积分、颈总动脉内径及颈动脉内-中膜厚度(intima-media thickness,IMT)。结果观察组斑块总发生率为88.52%,高于对照组33.33%,差异具有统计学意义(P<0.05),其中软斑块最为常见,所占比例为37.36%,其次为混合斑块、硬斑块、扁平斑块;双支病变组及多支病变组斑块积分、颈动脉IMT、颈总动脉内径均高于单支病变组,多支病变组斑块积分高于双支病变组,差异具有统计学意义(P<0.05),颈动脉IMT、斑块积分、颈总动脉内径随病变支数增加而增加,颈动脉病变程度与冠状动脉病变程度呈正相关。结论超声检测可有效显示颈动脉粥样硬化与冠状动脉粥样硬化程度,颈动脉粥样硬化与冠状动脉粥样硬化密切相关,并随冠状动脉粥样硬化程度加重而加重。 Objective To investigate the relationship between carotid atherosclerosis and coronary atherosclerosis in patients with ischemic stroke / transient ischemic attack by ultrasonography. Methods A total of 122 patients with ischemic stroke / transient ischemic attack admitted to our hospital from April 2014 to March 2016 were selected as the observation group, of which 61 patients with coronary atherosclerosis were Group A, and 120 patients In the same period, healthy people were taken as the control group, all underwent carotid ultrasonography. Carotid plaque incidence and plaque type were observed and compared. The plaque score, carotid artery internal diameter, Intima-media thickness (IMT). Results The total incidence of plaque in the observation group was 88.52%, which was higher than that in the control group (33.33%), the difference was statistically significant (P <0.05), of which soft plaque was the most common, accounting for 37.36%, followed by mixed plaque, Plaque, flat plaque, double-vessel lesion group and multi-vessel lesion plaque score, carotid artery IMT, common carotid artery diameter were higher than single-vessel disease group, multi-vessel disease group plaque score higher than the double-vessel disease group , The difference was statistically significant (P <0.05). The carotid artery IMT, plaque score and carotid artery internal diameter increased with the increase of lesion count. The degree of carotid artery lesion was positively correlated with the degree of coronary artery lesion. Conclusion Ultrasound can effectively show the degree of carotid atherosclerosis and coronary atherosclerosis, carotid atherosclerosis and coronary atherosclerosis are closely related, and aggravated with the severity of coronary atherosclerosis.
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