论文部分内容阅读
采用免疫组化技术连续对我院８２例传统检查无远处转移且行手术治疗的乳腺癌患者，进行骨髓内上皮膜抗原（ＥＭＡ）和（或）角蛋白（ＫＴ）表达细胞的测定，６８例得到随访。结果发现，骨髓阳性患者２８例５年生存率仅为２５％，而４０例骨髓阴性患者高达８５％，两者差别明显（Ｐ＜０．００５）。此外，骨髓阳性与预后指标如腋淋巴结状态、临床分期有密切联系。研究表明，该方法判断乳腺癌预后敏感、特异、直接，是检测乳腺癌微小转移的好方法。同时该方法对术后综合治疗的选择有一定的指导意义。
Using immunohistochemical techniques, 82 patients with breast cancer who had no distant metastasis and undergone surgical treatment in our hospital were examined for the presence of intraepithelial epithelial membrane antigen (EMA) and/or keratin (KT)-expressing cells in 68 patients. Followed up. The results showed that the 5-year survival rate of 28 patients with bone marrow-positive patients was only 25%, and that of 40 patients with bone marrow-negative patients was as high as 85% (P<0.005). In addition, bone marrow positivity is closely related to prognostic indicators such as axillary lymph node status and clinical stage. Studies have shown that this method is sensitive, specific, and direct to determine the prognosis of breast cancer and is a good method for detecting micrometastasis in breast cancer. At the same time, this method has certain guiding significance for the choice of postoperative comprehensive treatment.