论文部分内容阅读
目的探讨糖尿病(DM)椎体束、周围感觉、运动及自主神经功能。方法应用经皮层、脊髓电刺激运动诱发电位(MEP)、神经传导速度(NCV)及交感神经皮肤反应(SSR)技术对50例DM进行观察。结果MEP异常率82%(41/50),表现皮层、脊髓刺激MEP潜伏期延迟、波形分化欠佳,部分伴有中枢运动传导时间(CMCT)异常;NCV异常率70%,主要表现运动神经传导速度(MCV)延迟占65%(260/400),感觉神经传导速度(SCV)延迟占75%(150/200);SSR异常率76%(38/50),主要表现潜伏期延迟及波幅减低。MEP、NCV、SSR异常率与病程长短呈正相关;空腹血糖水平对MEP、NCV、SSR结果无明显影响。结论 DM患者的锥体束及周围感觉运动神经、自主神经功能均存在明显异常。MEP结合NCV、SSR可对DM的中枢及周围神经系统功能提供全面客观指标。
Objective To investigate the effects of diabetic (DM) vertebral body bundle, peripheral sensory, motor and autonomic nervous system. Methods Fifty cases of DM were observed by transthoracic electrical stimulation (MEP), nerve conduction velocity (NCV) and sympathetic skin reaction (SSR). Results The anomalous rate of MEP was 82% (41/50). The cortical and spinal cord stimulation delayed the latency of MEP, poorly differentiated waveform and partly accompanied with abnormal CMCT. The abnormality rate of NCV was 70%, mainly showing motor nerve conduction velocity (MCV) delayed 65% (260/400), sensory nerve conduction velocity (SCV) delayed 75% (150/200), SSR abnormal rate 76% (38/50), the main manifestations of delayed latency and reduced amplitude. The abnormal rates of MEP, NCV and SSR were positively correlated with the duration of the disease. Fasting plasma glucose had no significant effect on the results of MEP, NCV and SSR. Conclusion The pyramidal tract and peripheral sensory motor nerves and autonomic nervous functions of DM patients are obviously abnormal. MEP combined with NCV, SSR can provide a comprehensive and objective indicator of DM’s central and peripheral nervous system function.