通常认为肠道疾病可此起周围神经病和小脑疾病,但痴呆则常作为独立疾病来认识,作者对5例60岁以前患痴呆的病人进行追踪观察研究,发现肠道疾病可引起脑萎缩和早老性痴呆。病人和方法本组病人诊断时年龄为37～58岁。所有病人均作了有关诊断痴呆的实验室检查,包括甲状腺、肝、肾疾病的检查和血浆生心肌磷脂、维生素 B_(12)、铁含量和红细胞叶酸 It is generally thought that intestinal diseases can cause peripheral neuropathy and cerebellar diseases, but dementia is often recognized as an independent disease. The authors followed up 5 patients with dementia before the age of 60 and found that intestinal diseases can cause brain atrophy and premature aging Dementia. Patients and methods The age of this group of patients diagnosed 37 to 58 years old. All patients had laboratory tests for the diagnosis of dementia, including examination of thyroid, liver and kidney disease and plasma cardiolipin, vitamin B 12, iron content and erythrocyte folic acid