美国发病率和死亡率高的主要原因之一是血栓性栓塞,它的死亡率比癌症高5倍。尽管人们已成功地认识了凝血过程,血栓性栓塞仍不少见,显然与人类寿命延长有关。 1846年(?)提出了关于周围静脉的血块可栓塞肺动脉的设想。这一设想为体外研究血液凝固奠定了基础。他认为血凝的最重要阶段是血栓形成。在他看来,血管直径、血管壁以及血液流速,尤其是它们在动脉硬化时的改变,都具有很大作用。 60年后,Morawitz于1905年发表的一篇 One of the major causes of morbidity and mortality in the United States is thrombotic embolism, which has 5 times more mortality than cancer. Although people have successfully recognized the process of coagulation, thrombotic embolism is still not uncommon, obviously associated with prolonged human life expectancy. In 1846 (?) Put forward the idea of ​​the peripheral vein of the clot can be plugged pulmonary artery. This idea laid the foundation for the study of blood coagulation in vitro. He believes that the most important stage of blood clotting is thrombosis. In his view, blood vessel diameter, blood vessel wall and blood flow rate, especially their changes in arteriosclerosis, have a great role. Sixty years later, Morawitz published an article in 1905