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为探讨宫内病毒与弓形体感染对围产新生儿致畸及生长发育的影响，本文应用ＰＣＲ 技术对５４ 例活产畸形围产生儿进行了腺病毒（ａｄｒｅｎｏｖｉｒｕｓ，Ａｄｖ）、副流感病毒（ｐａｒａｉｎｆｕｌｕｅｎｚａｖｉｒｕｓ，Ｐｉｖ）、柯萨奇病毒（ｃｏｘａｃｋｉｅｖｉｒｕｓ，Ｃｏｘｖ）、巨细胞病毒（ｃｙｔｏｍｅｇａｌｏｖｉｒｕｓ，Ｃｍｖ） 、微小病毒Ｂ１９（ｐａｒｖｏｖｉｒｕｓ Ｂ１９ ，ＰｖＢ１９） 、及弓形体（Ｔｏｘｏｐｌａｓｍａ，Ｔｏｘｏ） 等抗原ＤＮＡ 检测。结果表明，中枢神经及心血管畸形抗原ＤＮＡ阳性率为６０．８７％ ，其它畸形抗原ＤＮＡ阳性率为２５ ．８１ ％ ，两组Ｐ＜ ０．０５。生后一个月时抗原ＤＮＡ阳性者生长发育落后率为６８ ．１８ ％ ，６ 个月时抗原ＤＮＡ 阳性率为７０ ．００ ％ ，二组生后１ 个月、６ 个月抗原ＤＮＡ 阳性组比较，Ｐ＜０．０１。建议孕母感染病毒时，应进行监控，必要时终止妊娠。
In order to investigate the effects of intrauterine virus and toxoplasmosis on the teratogenicity and growth of newborn infants, 54 cases of live-born deformity were diagnosed as adrenovirus (Adv), parainfluenza virus , Piv), Coxv, Cytomegalovirus (Cmv), parvovirus B19 (PvB19) and Toxoplasma antigen. The results showed that the positive rate of central nervous and cardiovascular malformation antigen DNA was 60.87%, other deformity antigen DNA positive rate of 25. 81%, two groups P <0.05. Antigen DNA positive one month after birth, the growth and development of the backward rate of 68. 18%, 6 months antigen DNA positive rate of 70. 00%, one month after birth, two groups after 6 months antigen DNA positive group, P <0.01. Proposals pregnant mothers infected with the virus should be monitored, if necessary, terminate the pregnancy.