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虽然免疫球蛋白于多种肾病者的肾小球沉着已被证实,但沉着抗原的性质证实得尚少,主要限于细菌、病毒或真菌的抗原。作者报告1例慢性淋巴性甲状腺炎合并肾病综合征,于患者肾小球检出了甲状腺球蛋白与微粒体抗原。患者经丙硫氧嘧啶与甲状腺制剂治疗4年,甲状腺仍渐肿大而t行部分切除,病理诊断为慢性淋巴性甲状腺炎。1年多后发生肾病综合征,遂入院治疗。
Although immunoglobulin has been demonstrated in glomerulonephritis in a variety of nephrotic subjects, the antigenic nature of the sedative antigen has been demonstrated to be rare, largely confined to bacterial, viral or fungal antigens. The authors report a case of chronic lymphocytic thyroiditis with nephrotic syndrome, thyroglobulin and microsomal antigens were detected in patients with glomerulus. Patients treated with propylthiouracil and thyroid preparations for 4 years, the thyroid is still swollen and large part of the tumor removed, the pathological diagnosis of chronic lymphocytic thyroiditis. More than 1 year after the occurrence of nephrotic syndrome, then hospitalized.