论文部分内容阅读
目的:通过分析头孢菌素类抗生素所致的ADR,了解该类药物ADR的特点与一般规律,为临床合理用药提供参考,以减少ADR的发生。方法:采用回顾性调查方法,对某院2010年1月-2011年12月收到的头孢菌素类抗生素ADR病例报告进行统计分析。结果:385例头孢菌素类抗生素ADR病例报告中,共涉及药品14种,排前3位的是头孢曲松(116例)、头孢噻肟(68例)、头孢哌酮(50例);以静脉给药最常见,其次为肌肉注射;共累及人体的9个系统,损害最多的为皮肤及其附件。结论:头孢菌素类抗生素ADR发生比较常见,对人体危害大,应高度重视对ADR的监测,以提高合理用药水平。
OBJECTIVE: To understand the characteristics and general rules of ADR caused by cephalosporin antibiotics by analyzing the ADR caused by cephalosporin antibiotics, to provide a reference for clinical rational drug use to reduce the occurrence of ADR. Methods: A retrospective survey was conducted to analyze the reports of cephalosporin antibiotic ADR cases received in a hospital from January 2010 to December 2011. Results: Of the 385 cases of cephalosporin antibiotics, 14 kinds of drugs were reported in the ADR cases, the top three were ceftriaxone (116 cases), cefotaxime (68 cases) and cefoperazone (50 cases). The most common intravenous administration, followed by intramuscular injection; a total of nine systems involving the human body, the most damaging of the skin and its annexes. Conclusion: The occurrence of cephalosporin antibiotics ADR more common, harmful to human body, we should attach great importance to the monitoring of ADR in order to improve the reasonable level of medication.