论文部分内容阅读
目的:探讨滥用氯胺酮所引起的泌尿系统损害及诊治方法。方法:回顾性分析56例有滥用氯胺酮史患者的泌尿系统症状、体征、泌尿系统相关检查,根据不同情况予以相关治疗方案的探讨。结果:氯胺酮相关性泌尿系统损害主要症状为下尿路症状(LUTS),膀胱病理活检表现为不同程度的炎症改变。影像学检查可见不同程度的病变,主要表现为:膀胱容量小,膀胱壁增厚,膀胱挛缩,输尿管狭窄,肾积水。3例患者血清肌酐升高。结论:氯胺酮相关性泌尿系统损害是以下尿路症状(LUTS)为主要临床表现的疾病,疾病早期为可逆性,治疗效果良好,后期继发的膀胱挛缩和肾功能损害是不可逆的,需要引起重视。
Objective: To explore the abuse of ketamine caused by urinary tract damage and diagnosis and treatment methods. Methods: A retrospective analysis of 56 cases of history of abuse of ketamine in patients with urinary tract symptoms, signs, urinary system related tests, according to different situations to be related to the treatment of the program. Results: The main symptoms of ketamine-associated urinary system damage were lower urinary tract symptoms (LUTS) and bladder biopsy showed varying degrees of inflammatory changes. Imaging examination showed varying degrees of disease, mainly as follows: small bladder capacity, bladder wall thickening, bladder contracture, ureteral stricture, hydronephrosis. Serum creatinine increased in 3 patients. CONCLUSION: Ketamine-related urinary tract injury is a disease characterized by the following clinical manifestations of urinary tract symptoms (LUTS). Early disease is reversible and has good therapeutic effect. Bladder contracture and renal dysfunction secondary to subsequent infection are irreversible and require attention .