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目的探讨急性脑卒中患者入院血糖水平与住院期间发生死亡、残疾的关系。方法收集内蒙古通辽市6家医院2003年1月~2005年12月的3 938例脑卒中患者基线资料,进行血糖检测;采用Logistic回归模型进行统计分析。结果调整了年龄、性别、民族、吸烟史、饮酒史及血压后,入院血糖≥7.0 mmol/L组的脑卒中患者住院期间发生死亡的OR为8.227(95%CI=4.122~16.420),发生复合结局(死亡或残疾)的OR为2.043(95%CI=1.494~2.793)。趋势检验分析结果显示,脑卒中患者住院期间发生死亡和复合结局(死亡或残疾)的危险性有随着入院血糖水平升高而增高的趋势。结论入院高血糖可能是脑卒中患者住院期间死亡及复合结局的独立危险因素,应在急性期积极控制血糖水平。
Objective To investigate the relationship between the incidence of death and disability during hospital admission in patients with acute stroke. Methods The baseline data of 3 938 stroke patients from January 2003 to December 2005 in 6 hospitals of Tongliao City of Inner Mongolia were collected for blood sugar testing. Logistic regression model was used for statistical analysis. Results After adjustment for age, sex, ethnicity, smoking history, drinking history and blood pressure, the odds of death from hospitalization during hospital admission for blood glucose> 7.0 mmol / L were 8.227 (95% CI = 4.122-16.420) The OR for outcome (death or disability) was 2.043 (95% CI = 1.494-2.793). Trend test analysis showed that the risk of death and composite outcome (death or disability) during stroke in hospitalized stroke patients tended to increase with increasing admission glucose levels. Conclusion Admission of hyperglycemia may be an independent risk factor for death and composite outcome during hospitalization in stroke patients. Positive blood glucose level should be controlled in acute phase.