结构紊乱(Ds)是在实验室鼠类中的一种常染色体显性突变,是偶发先天畸形的一个模型。在鼠Ds中最具特征性的畸形是体表有各种凸出物,例如错构瘤,包括分化较好的组织构成的结节和乳头状突起。也可见到额外的肢体和肢端畸形。体壁缺损包括腹裂畸形、胸裂畸形,并且已看到有各种内脏器官的畸形。 Structural disorder (Ds) is an autosomal dominant mutation in laboratory mice that is a model of sporadic congenital malformations. The most characteristic deformity in the rat Ds is the presence of various bulges on the body surface, such as hamartomas, including well-differentiated nodules and papillae. Additional limb and limb deformities can also be seen. Body wall defects include gastroschisis, thoracic spondylosis, and have seen deformities of various internal organs.